Canadian scientists have uncovered a single genetic mutation that significantly heightens a person’s chance of developing a progressive and severe form of multiple sclerosis. While no single factor is responsible for causing the neurological disease, the discovery points to possible treatment options.
A surprising new genetic study shows that some people with naturally high levels of HDL cholesterol—the supposedly good kind of cholesterol—are at increased risk of a heart attack. Doctors are now further questioning the use of drugs to boost HDL levels while looking to new therapies to reduce heart risk.
For the people with this genetic defect, HDL (“good”) cholesterol is not good because the defect destroys their liver’s ability to absorb fat brought to it by HDL. In normal people, HDL still correlates with lower risk of heart disease.
Birds have a quality known as broodiness. It means that, after they lay their eggs, they stick around and take care of those eggs. Most commercial chickens don’t have that quality. And it looks like their complete disregard for their offspring results from one genetic mutation.
Having raised chickens, both for meat and eggs, I never thought about this. I’ve certainly seen broodiness in other fowl, like geese and ducks. You only have to get bitten by a goose once… Not me, I just watched 😀
The “good genes hypothesis” provides an appealing explanation of this finding. It argues that deviation from facial symmetry is due to difficulties arising during development caused by malnutrition, infection or genetic mutation. The degree of facial symmetry may therefore be a marker of health and resilience, indicating how well people cope with environmental or genetic challenges. So we may find facial symmetry desirable in a mate because these qualities prove beneficial to potential offspring.
I’m not getting stronger – just better muscle definition as my body fat percentage decreases. But we correlate muscle visibility with gym/exercise… We’re also seeing people who have low body fat/BMI, but bad cholesterol, blood pressure, etc because they aren’t triggered to review their health because they aren’t getting fat.