Scientists Find Cure For Type 2 Diabetes in Rodents, Don’t Know How it Works

The cure for type 2 diabetes may be all in your head, a new study in rats and mice suggests.

With a single shot to the brain, researchers can rid rodents of all symptoms of the disease for months. The injection, a relatively low dose of a tissue growth factor protein called fibroblast growth factor 1 (FGF1), appears to reset powerful neural networks that can control the amount of sugar in the blood.

Source: Scientists find cure for type 2 diabetes in rodents, don’t know how it works

Oh sure. When some guy in a lab coat injects something into a rodent’s brain it’s call “science”. When try to inject something into a bear’s arm I get banned from the zoo and arrested for having heroin.

Advertisements

A Common Artificial Sweetener Is Poisoning Dogs

Xylitol is an artificial sweetener found in everything from toothpaste to peanut butter to sugar-free gum. And, it turns out, it’s poison for dogs.

Source: A Common Artificial Sweetener Is Poisoning Dogs

It’s not peanut butter/etc per se – it’s the artificial sweetener in certain brands when they want to make it low calorie.   So it might just be a small amount of the wrong kind.

Off-Switch For Overeating and Obesity Found in the Brain

After tediously tracking calories and willfully shunning cravings, many a dieter has likely dreamt of a simple switch that, when thrown, could shut down hunger and melt away pounds—and scientists may have just found it.

Source: Off-switch for overeating and obesity found in the brain

The “it’s your own fault” view of obesity as a willpower issue does not hold up to logical scrutiny.

As far as I know, obesity is the only condition that has massively increased in humans, despite an overwhelmingly negative view of it by society, and shaming of sufferers. Look at smoking as an analog–despite how difficult it is to quit smoking, people have done so in huge numbers over the past few decades, while obesity has continued to rise, unabated, throughout the world. If it were a willpower issue, as smoking apparently is, we would most certainly not see this happening.

Stem Cell Breakthrough Could Put an End to Daily Insulin Injections for Diabetics

People with type 1 diabetes have to inject insulin daily, and it often results in pain, redness, swelling, and itching at the injection site. But this could soon be a thing of the past, thanks to a new breakthrough that takes us one step closer to a functional cure for type 1 diabetes.

Source: Stem Cell Breakthrough Could Put an End to Daily Insulin Injections for Diabetics

Sounds promising. However, type 1 diabetes is an autoimmune disease, wherein one’s immune system attacks and kills the insulin producing cells in one’s pancreas. I wonder what will keep the immune system from going haywire a second time. I am guessing they are on that too.

Diabetic Woman Becomes First in the World to Receive Pancreas Transplant Because of Needlephobia

A British woman has become the first person in the world to have a pancreas transplant because of a severe needle phobia, her doctors have said.

Sue York – who has had type-1 diabetes since she was seven – would shake uncontrollably and vomit when injecting herself with insulin.

Source: Needle-phobic pancreas transplant ‘world first’

I’m glad she was able to get the surgery and end her suffering.

The article doesn’t mention it, but I thought most transplants required the patient to take anti-rejection drugs for the rest of their lives. These drugs are generally oral, but require regular blood testing to ensure correct levels. That doesn’t seem to be the case here, or she would just be swapping one kind of needle for another (albeit less frequent), somewhat defeating the purpose of the surgery.  A blood test once or twice a month isn’t really comparable to the daily contact diabetics have with needles.

I was recently waiting for my turn to test my INR, listening to someone’s child who was freaking out about getting a needle for some reason.  That would have been me until I was put on warfarin/coumadin.  Weekly testing eradicated the issue for me, but I clearly did not suffer like this woman.  For me, testing weekly meant alternating arms.  Daily testing is awful, but I find it odd that she managed for so long.

Temporarily Quitting Alcohol Brings Health Benefits

“DRY January”, for many a welcome period of abstinence after the excesses of the holiday season, could be more than a rest for body and soul. New Scientist staff have generated the first evidence that giving up alcohol for a month might actually be good for you, at least in the short term.

Many people who drink alcohol choose to give up for short periods, but there is no scientific evidence that this has any health benefits. So we teamed up with Rajiv Jalan at the Institute for Liver and Digestive Health at University College London Medical School (UCLMS) to investigate.

Source: Our Liver Vacation: Is a Dry January Really Worth It?

The study is small and informal, but it fits with what we know about how alcohol works on our bodies. Rather than quitting for a month and then going back on your usual schedule, it’s probably better to use this as a lesson in how easy it is to reverse some of the effects of alcohol.

How Hormones Make You Feel Hungry and Full

The need to find fuel to generate energy is a profound drive within the biology of all living organisms: we all need food to survive. So it’s not surprising that our bodies have such a complex system to control food intake, driven by hormones.

Source: How Hormones Make You Feel Hungry and Full

Interesting to learn that the food cravings after/during weight loss are hormonal.

Are Energy Drinks Bad for You?

Red Bull may give you wings, but at what cost? To some, energy drinks are dangerous elixirs, while others consider them magic potions of vitality? The truth about how they affect your body is not so black and white.

Source: Are Energy Drinks Bad for You?

I’ve never had an energy drink.  Closest thing would be a Gu gel…

The specific mention about long term ginseng use is interesting with the mention about impact to blood thinners.  Ginger is a low dose of vitamin K, ginseng is entirely different.

Quebec Strawberry has Potential to Reduce Type 2 Diabetes Risk

Quebec may be known for maple syrup and poutine, but perhaps soon strawberries can be added to the list. A varietal known as the Authentic Orleans strawberry appears to help reduce the risk of developing Type 2 diabetes.

Source: Quebec strawberry has potential to reduce Type 2 diabetes risk

Don’t go running out for strawberries just yet.  The findings are preliminary, but more fruit & veg is always a good idea.

8 Things That Happen When You Finally Stop Drinking Diet Soda

You’ve decided to give up diet soda—good idea! Maybe you weren’t hitting your weight-loss goals or couldn’t stomach that long list of ingredients anymore. Or perhaps you heard one too many times that it’s just not good for you.

Whatever the reason, eliminating diet soda from your diet will improve your health from head to toe. Research on diet soda is still in its infancy, but there’s enough out there to identify what you can look forward to when you put down the can and cool down with an unsweetened iced tea instead.

Source: 8 Things That Happen When You Finally Stop Drinking Diet Soda

Sorry, but soda/pop is one place I will not consider the diet alternative.  Simply due to taste – most just prompted me to drink water instead (for the best anyway, but not for Big Soda/Pop).

The aspect of weight loss because of coming off diet soda/pop isn’t that surprising.  It’s often suggested that we consume more because we’re under the impression the food/beverage is healthier so we can consume more. As the joke goes: I’ll have the extra large burger, extra large fries, and …a diet soft drink.